South Eastern Region Vacations & Trips from $1,327

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Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

Top destinations in South Eastern Region

Valletta which includes a city, a sunset and heritage architecture
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Valletta

Valletta

The Latest South Eastern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Iniala Harbour House

Iniala Harbour House

5 out of 5
Save 100% on your flight
Price was $2,055, price is now $1,327 per person
$1,327
per person
Nov 15 - Nov 20
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Luqa (MLA)
9.8/10 Exceptional! (98 reviews)
This hotel is one of the best we’ve ever stayed at. The staff were beyond excellent. Our room overlooking The Grand Harbour had 3 balconies. The views were amazing.

Reviewed on Sep 17, 2025

Rosselli

Rosselli

5 out of 5
Price was $2,570, price is now $2,069 per person
$2,069
per person
Dec 20 - Dec 27
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.4/10 Exceptional! (52 reviews)
Very comfortable rooms. Staff were very helpful. Central location, easy walk to the harbour

Reviewed on Aug 20, 2025

The Gomerino Hotel

The Gomerino Hotel

4 out of 5
Price was $2,145, price is now $1,772 per person
$1,772
per person
Dec 20 - Dec 27
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.6/10 Exceptional! (896 reviews)
Good location. Very clean.Attentive service. Room are very small.

Reviewed on Sep 27, 2025

AX The Heights Residences

AX The Heights Residences

4 out of 5
Price was $5,298, price is now $4,397 per person
$4,397
per person
Dec 20 - Dec 27
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
No reviews
San Karlu Hotel

San Karlu Hotel

4 out of 5
Price was $2,206, price is now $1,838 per person
$1,838
per person
Dec 20 - Dec 27
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.4/10 Exceptional! (163 reviews)
New property in quiet location

Reviewed on Sep 27, 2025

Where to stay in South Eastern Region

Get a lay of the land and find the perfect place to stay Learn more about South Eastern Region
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San Tumas

When in San Tumas, you can plan a visit to St. Peter's Pool and Pretty Bay, some noteworthy sights in the nearby area.

Find hotels in San Tumas

South Eastern Region Hotel Deals

Grand Hotel Excelsior

Grand Hotel Excelsior

5 out of 5
Great Siege Road, Floriana, Malta
$264 nightly
The price is $284 total per night from Oct 25 to Oct 26
$284 total
Oct 25 - Oct 26
Total with taxes and fees
8.6/10 Excellent! (1,017 reviews)
"Great hotel. Chose this because of facilities and location to beach. Can’t find a better hotel with such great beach access - spent most of our time there. Will come back again"

Reviewed on Sep 21, 2025

Grand Hotel Excelsior
The Gomerino Hotel

The Gomerino Hotel

4 out of 5
247 St Paul St, Valletta
Fully refundableReserve now, pay when you stay
$325 nightly
The price is $349 total per night from Oct 23 to Oct 24
$349 total
Oct 23 - Oct 24
Total with taxes and fees
9.6/10 Exceptional! (905 reviews)
"Great hotel so great to have a pool in the city we loved our stay! Close to cafes, bars and restaurants."

Reviewed on Sep 25, 2025

The Gomerino Hotel
Palais Le Brun

Palais Le Brun

4.5 out of 5
101 old bakery street, Valletta
$292 nightly
The price is $314 total per night from Oct 3 to Oct 4
$314 total
Oct 3 - Oct 4
Total with taxes and fees
9.4/10 Exceptional! (762 reviews)
"Nice breakfast. Great location."

Reviewed on Sep 25, 2025

Palais Le Brun
See all 940 properties in South Eastern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in South Eastern Region

Malta Experience

Malta Experience

Enjoy a show at Malta Experience, a storied theater in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.

Malta Experience
Beautiful view from Sliema Ferry station to Valletta. If you stay in a hotel in Sliema it only needs 5 minutes with the Sliema Ferry to Valletta. Very fast and easy. A return ticket costs 2.80 Euro.

Sliema Ferry

Explore the waterfront in Valletta with a trip to Sliema Ferry. Wander the area's seaside or simply enjoy one of its top-notch restaurants.

Sliema Ferry
View from inside of a cathedral in Valletta, Malta. The St. John’s Co-Cathedral is a cathedral decorated in baroque style. This is a view of the altar.

St. Johns Co - Cathedral

After visiting St. Johns Co - Cathedral, make a plan to see the other sights and activities in Valletta. Wander the area's seaside or simply enjoy one of its top-notch restaurants.

St. Johns Co - Cathedral

What to do in South Eastern Region

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

$35
per adult
88% of travellers recommend
Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour
From Malta: Malta, Gozo & Comino Three Islands Sailing Trip

Malta: Blue Lagoon, Crystal Lagoon & Comino and Sea Caves

$35
per adult
Malta: Blue Lagoon, Crystal Lagoon & Comino and Sea Caves
Mv Kataleya

Gozo, Comino and Blue lagoon Cruise

$47
per adult
84% of travellers recommend
Gozo, Comino and Blue lagoon Cruise
See all activities in South Eastern Region
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