South Eastern Region Vacations & Trips from $570

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Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

Top destinations in South Eastern Region

The Latest South Eastern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Cinematique
Hotel Levante St. Julian's, Affiliated by Meliá
Mosta Dome B&B
Riviera Spa Resort – Adults Only
Onyx Hotel

Where to stay in South Eastern Region

Get a lay of the land and find the perfect place to stay Learn more about South Eastern Region

Find the Best South Eastern Region Vacation Packages

South Eastern Region Essential Information

Language
Maltese
Currency
Euros
Local Welcome
Hawn
Local Goodbye
Ċaw
Top Sights
Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay

South Eastern Region Hotel Deals

Grand Hotel Excelsior

Grand Hotel Excelsior

5 out of 5
Great Siege Road Floriana Malta
Fully refundableReserve now, pay when you stay
$265 nightly
The price is $285 total per night from May 30 to May 31
$285 total
May 30 - May 31
Total with taxes and fees
8.8/10 Excellent! (1,017 reviews)
A nice clean room, cleaned often throughout the stay. Great pool and facilities. Friendly helpfull staff, amazing selection of quality food at breakfast, dinner menus were great too we could not fault the place.

Reviewed on May 12, 2026

Grand Hotel Excelsior
La Falconeria Hotel

La Falconeria Hotel

3 out of 5
62 Melita Street Valletta
Fully refundableReserve now, pay when you stay
$250 nightly
The price is $268 total per night from May 20 to May 21
$268 total
May 20 - May 21
Total with taxes and fees
9.4/10 Exceptional! (1,008 reviews)
Reception personnel were very helpful. Made a great suggestion for lunch. (Corkney's near Sliema Ferry)

Reviewed on May 9, 2026

La Falconeria Hotel
San Karlu Hotel

San Karlu Hotel

4 out of 5
28 Saint Charles Street Valletta South Eastern Region
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $239 total per night from May 13 to May 14
$239 total
May 13 - May 14
Total with taxes and fees
9.4/10 Exceptional! (259 reviews)
Since the hotel is located on the side street, there’re some steps to getting down and up to: from the hotel. It’s very quiet but 10 mins walk to Republic Square. Many restaurants and busy area nearby. The room we stayed has a tiny window which can’t see anything or use it properly. So the room is ...

Reviewed on Apr 30, 2026

San Karlu Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in South Eastern Region

What to do in South Eastern Region

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